Page 1 of 7 paraformaldehyde cas no 30525894 material safety data sheet sds msds section 1. If inhaled if breathed in, move person into fresh air. Paraformaldehyde revision date 18jan2018 component casno weight % paraformaldehyde 30525894 90 4. Paraformaldehyde is on the right to know hazardous. Pdf aldehydes are the most commonly used fixatives. Paraformaldehyde revision date 14apr2016 general advice if symptoms persist, call a physician. Paraformaldehyde has documented uses as a disinfectant, fungicide, fixation reagent and in the preparation of formaldehyde. Paraformaldehyde solution 4% in pbs cas 30525894 scbt. Identification product name formalin, buffered, 10% phosphate buffercertified cat no. Beware though, that some solutions have methanol in them to stop polymerization but this could have a negative effect on your sample. No warranty, express or implied, is made and labchem inc.
Identification of the substancemixture and of the companyundertaking. None information in this msds is from available published sources and is believed to be accurate. Show this safety data sheet to the doctor in attendance. Collect liquid in an appropriate container or ab sorb with an.
Paraformaldehyde 1 10 30525894 ingredient name % cas number there are no additional ingredients present which, within the current knowledge of the supplier and in the. Paraformaldehyde, formadehyde and formalin duke light. Material safety data sheet product name formalin solution 10 % neutral buffproduct code 28600 section 8. Formaldehyde, the decomposition product of paraformaldehyde, has been listed as a carcinogen by ntp and iarc. While paraformaldehyde has not been identified as a carcinogen, it should be handled with. In cell culture, a typical formaldehyde fixing procedure would involve using a 4% formaldehyde solution in phosphate buffered saline pbs on ice for 10 minutes. Paraformaldehyde reagentgrade,crystalline 30525894. Inflammation of upper respiratory tract tissue was noted in these groups.
We are happy to announce that we are fully compliant with ghs requirements domestically as well as internationally. It is electron microscopygrade paraformaldehyde dissolved in ph 7. Sheet msds and the label to determine product ingredients. Eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Safety data sheet northwest missouri state university. Page 17 safety data sheet according to 19072006ec, article 31 printing date 19. Formaldehyde,the decomposition product of paraformaldehyde, has been listed as a carcinogen by ntp and iarc. Uses advised against food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet emergency telephone number. Find msds or sds, a coa, data sheets and more information. Harmful if swallowed, in contact with skin or if inhaled. Formaldehyde was also present at concentrations of 3. The user must determine suitability of this information for his application. Paraformaldehyde revision date 18jan2018 polymer made with any freeradical initiator regardless of the amount used. Paraformaldehyde is the polymeric form of formaldehyde.
Paraformaldehyde, 4% in pbs, readytouse fixative biotium. Formaldehyde is a gas which when dissolved in water gives a formaldehyde solution. Firstaid measures general advice if symptoms persist, call a physician. Page 4 of 10 msds formaldehyde unprotected personnel from entering. Formalin 10% safety data sheet date of issue 26022007. Eliminates the step of depolymerization paraformaldehyde prior to use. Methylene oxide, ac4553, ac4554, 41860, 41883 supplier.
Sigmaaldrich offers a number of paraformaldehyde products. Paraformaldehyde solution 4% in pbs is commonly used to preserve tissues for routine histology in many labs. Ultra pure, methanol free, 10 % aqueous formaldehyde is suitable for both electron and light microscopy. If your lab is not a regular user of formaldehyde fixatives, there are a couple of easier options that we recommend. Formaldehyde, formalin, paraformaldehyde and glutaraldehyde. Exposure controls, personal protection engineering controls use of a fume hood is recommended. It is commonly used in tissue fixing and preservation, and as an organic chemical reagent. Formaldehyde, 10%, methanol free, ultra pure polysciences, inc. Protocol for making a 4% formaldehyde solution in pbs. Pure, methanolfree formaldehyde can be made by heating the solid.
Formalin 10 % safety data sheet date of issue 26022007. Respiratory protection if the exposure level is exceeded, wear a full facepiece respirator equipped with a formaldehyde cartridge. Exposure was stopped during the first week for the middle and high dose groups due to high mortality. In histology and pathology specimens preparation, usually, the fixation step is performed. Formaldehyde, 20% vv aqueous solution msds msdsdigital. Formaldehyde, formalin, paraformaldehyde safe work practices. Store in a cool, dry, wellventilated area away from incompatible substances. Hazards identification harmful by inhalation, in contact with skin and if swallowed. In case of contact with eyes flush immediately with plenty of flowing water for 10 to 15 minutes. Methanol is added to slow down the polymerization to formaldehyde, which reduces the fixing power of formalin. Repeated or prolonged exposure to the substance can produce target organs damage. Formalin can also be made in an alcoholfree form from powdered paraformaldehyde.
Sds complies with oshas hazard communication rule 29, cfr 1910. Paraformaldehyde, 4% in pbs is a readytouse fixation solution for cells or tissues. Our msds database is an easy to use, do it yourself tool, and best of all. Skin contact wash off immediately with plenty of water for at least 15 minutes. In fluorescence studies, paraformaldehyde has been used as as a formalin fixative to fix cells and tissues. Paraformaldehyde cas 30525894 emprove essential dac find msds or sds, a coa, data sheets and more information. One option is to purchase methanolfree formaldehyde aq in sealed ampoules. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database.
Formaldehyde solution 37 ww, stablized with 1012% methanol. Paraformaldehyde applications applications the most important use of paraformaldehyde is as a source of formaldehyde groups in the production of many thermosetting resins, together with phenol, urea, melamine, resorcinol and other similar reagents. Page 1 of 10 msds formaldehyde material safety data sheet msds formaldehyde 1. The solution should be clear, colorless, with no precipitate and the. A material safety data sheet has been issued describing the health, safety and. When used in combination with glutaraldehyde, it fixes delicate tissues such as brain in vascular perfusion. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Use precautions against formaldehyde exposure when opening containers or entering a poorly ventilated storage area. Sf1004, sf10020, sf100200 synonyms no information available recommended use laboratory chemicals.
In case of contact, immediately flush eyes with plenty of water for a t least 15 minutes. Commercially available formaldehyde solutions usually contain 10 15% methanol, which prevents the formaldehyde from forming the polymeric paraformaldehyde. P indicates a commenced pmn substance r indicates a substance that is the subject of a section 6 risk management rule under tsca. In case of contact, immediately flush skin with soap and plenty of water. Thus, a protocol calling for 10 % formalin is roughly equivalent to 4% formaldehyde. The most widely used formaldehydecontaining chemical at uw is 10 % neutral buffered nb formalin, which contains 4% formaldehyde.
Limited evidence of carcinogenicity in animal studies. Sara 3 notifications must not be detached from the sds and any copying and. How to generate formaldehyde from paraformaldehyde. Paraformaldehyde can be quite hazardous to handle and it is often difficult to get it to go into solution. Paraformaldehyde solution 4% in pbs cas 30525894 is rated 4. Refer to certificate of analysis for lot specific data including water content. Paraformaldehyde pfa is actually polymerized formaldehyde. I heated the paraformaldehyde to generate the formaldehyde and absorb it by dry thf, and got nothing.
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